HRX215, CAS 2369583-33-3

Shelf life (days): 1460

Info: An MKK4 inhibitor (IC50 = 0.02 µM); selective for MKK4 over JNK1, B-RAF, and MKK7 (IC50s = 7.07, 11.46, and 14.97 µM, respectively); decreases hepatocyte apoptosis in a mouse model of CCl4-induced liver damage at 10 mg/kg; increases survival and hepatic size and regeneration, decreases ICP, and reduces blood levels of ammonia, total bilirubin, and AST levels in a porcine model of partial hepatectomy-induced liver failure when administered at 5 mg/kg

Formulation: A solid

Formal Name: N-[2,6-difluoro-3-[[5-(4-pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]carbonyl]phenyl]-1-propanesulfonamide

Purity: ≥98%

Formula Markup: C21H17F2N5O3S

Formula Weight: 457.454386

CAS Number: 2369583-33-3

• Artikelnummer: CAY41238-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41238-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK