Background: Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation (PubMed:18165312). Receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]
Description: Human CML2-Strep full length protein-synthetic nanodisc
Molecular Weight: The human full length CML2-Strep protein has a MW of 41.4 kDa
Protein Families: GPCR,Transmembrane,Druggable Genome,
Protein Pathways: GPCRDB Class A Rhodopsin-like,
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Tag: C-Flag&Strep Tag
Expression Host: HEK293
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Target: CML2
Uniprot ID: P46091
Usage: Research use only
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