Human Kappa Light Chain (B-Cell Marker) (rL1C1), CF740 conjugate, 0.1mg/mL

Human Kappa Light Chain (B-Cell Marker) (rL1C1), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC742222-500
Verpackungseinheit
500 uL
Hersteller
Biotium

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Description: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: rL1C1

Immunogen: Human B-Lymphoma Cells

Antibody Reactivity: Human Kappa Light Chain

Entrez Gene ID: 3514

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Does not react with rat/Immunohistology (formalin): 0.5-1 ug/mL for 30 minutes at RT/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Optimal dilution for a specific application should be determined by user
Mehr Informationen
Artikelnummer BTMBNC742222-500
Hersteller Biotium
Hersteller Artikelnummer BNC742222-500
Verpackungseinheit 500 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Immunohistochemistry
Isotyp IgG1
Wirt Mouse
Konjugat Conjugated, CF740
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