Human LGR5-Strep full length protein-synthetic nanodisc

Human LGR5-Strep full length protein-synthetic nanodisc
Artikelnummer
DMAFLP120073-50
Verpackungseinheit
50 µg
Hersteller
DIMA Biotechnology

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Background: The protein is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

Description: Human LGR5-Strep full length protein-synthetic nanodisc

Molecular Weight: The human full length LGR5-Strep protein has a MW of 100 kDa

Protein Families: Druggable Genome, GPCR, Transmembrane

Protein Pathways: N/A

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Tag: C-Flag&Strep Tag

Expression Host: HEK293

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.

Target: LGR5

Uniprot ID: O75473

Usage: Research use only
Mehr Informationen
Artikelnummer DMAFLP120073-50
Hersteller DIMA Biotechnology
Hersteller Artikelnummer FLP120073-50
Verpackungseinheit 50 µg
Mengeneinheit STK
Konjugat Unconjugated
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MSDS (PDF) Download