Product Description: Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)[1].
Formula: C89H134N28O24S.xC2HF3O2
References: [1]Mummert ME, et al. Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking. J Exp Med. 2000 Sep 18;192(6):769-79.
Molecular Weight: 2012.25 (free base)
Compound Purity: 97.02
Research Area: Cancer; Inflammation/Immunology
Target: Transmembrane Glycoprotein
Deutsch
English
