Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 6-(trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide-3-13C-3,3-d2 1,1-dioxide
Purity: ≥99% deuterated forms (d1-d2)
Formula Markup: C7[13C]H6D2F3N3O4S2
Formula Weight: 334.3
CAS Number: 1189877-11-9
Notes: Hydroflumethiazide-13C-d2 is intended for use as an internal standard for the quantification of hydroflumethiazide (Item No. 23612) by GC- or LC-MS. Hydroflumethiazide is a thiazide diuretic and an inhibitor of carbonic anhydrase (CA).{23242} It is selective for CAII, CAVB, CAVII, CAIX, CAXII, and CAXIV (Kis = 0.24-0.31 µM) over CAI, CAIV, and CAVI (Kis = 2.8-8.3 µM), as well as CAIII, CAVA, and CAXIII (Kis = >10 µM). Formulations containing hydroflumethiazide have been used in the treatment of hypertension.