Product Description: Hydroxyzine, a benzodiazepine antihistamine agent, acts as an orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine has anxiolytic effect and can be used for the research of generalised anxiety disorder[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C21H27ClN2O2
References: [1]Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63./[2]Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979. 7(2): p. 173-80./[3]Nikita Shekhar Sawantdesai, et al. Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice. J Basic Clin Pharm. 2016 Sep;7(4):97-104.
CAS Number: 68-88-2
Molecular Weight: 374.90
Compound Purity: 99.72
Research Area: Inflammation/Immunology; Endocrinology
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 5 mg/mL (ultrasonic;warming;adjust pH to 4 with HCl;heat to 60°C)
Target: Histamine Receptor
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