(±)-Ibuprofen-d3, CAS 121662-14-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: a-(methyl-d3)-4-(2-methylpropyl)-benzeneacetic acid

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C13H15D3O2

Formula Weight: 209.3

CAS Number: 121662-14-4

Notes: (±)-Ibuprofen-d3 is intended for use as an internal standard for the quantification of ibuprofen by GC- or LC-MS. (±)-Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) and non-selective COX inhibitor (IC50s = 2.6 and 1.3 µM for human recombinant COX-1 and COX-2, respectively).{1364} In vivo, (±)-ibuprofen inhibits late-phase formalin-induced paw licking in mice (ED50 = 6.1 mg/kg).{57951} It also inhibits acetic acid-induced writhing in mice (ED50 = 0.47 mg/kg). Formulations containing (±)-ibuprofen have been used in the treatment of fever and mild to severe pain.

• Artikelnummer: CAY18255-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18255-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung