IDO-IN-2, CAS 1668565-74-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[4-[bis(2-methylpropyl)amino]-2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]-N'-(4-methylphenyl)-urea

Purity: ≥98%

Formula Markup: C29H35N7O

Formula Weight: 497.63478

CAS Number: 1668565-74-9

Notes: IDO-IN-2 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1; IC50 = 0.097 µM in HeLa cells).{61704} In vivo, IDO-IN-2 (100 mg/kg) decreases intratumor levels of Ki67, a marker of cell proliferation, and reduces tumor weight in a GL261 murine glioma heterotopic transplantation model.{61705} It also decreases mechanical and thermal hypersensitivity, improves novel object recognition, and decreases anterior cingulate cortex (ACC) and amygdala levels of IDO1 in a rat model of neuropathic pain induced by spinal nerve ligation (SNL).{61706}

• Artikelnummer: CAY34876-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34876-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK