IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody (HL3537)

Clone Name: HL3537

Light Chain: Kappa

Application Note: ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Uniprot ID: P08069

Antigen Species: Human

Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Tyr1131 of human IGF1R. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: insulin like growth factor 1 receptor

• Artikelnummer: GTX641434-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX641434-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 3480
• Wirt: Rabbit
• Konjugat: Unconjugated