Product Description: IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
Applications: Cancer-Kinase/protease
Formula: C26H23FN8O
References: [1]Guntuku L, et al. IITZ-01, a novel potent lysosomotropic autophagy inhibitor, has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo. Oncogene. 2018 Aug 30.
CAS Number: 1807988-47-1
Molecular Weight: 482.51
Compound Purity: 98.18
Research Area: Cancer
Solubility: DMSO : 150 mg/mL (ultrasonic)
Target: Apoptosis;Autophagy;PI3K