Description: IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor, which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development. IL-4 is expressed primarily by activated Th2 cells and NK cells, and at lower levels by mast cells, and basophils. IL-4 signals through the IL-4R, and dendritic cell IL-12. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Origin: Animal - Rattus norvegicus (laboratory rat), Bos taurus (bovine)
Conjugate: CF740
Concentration: 0.1 mg/mL
Storage buffer: PBS, 0.1% rBSA, 0.05% azide
Clone: 11B11
Immunogen: Partially Purified native Mouse IL-4
Antibody Reactivity: IL-4 ,
References: Note: References for this clone sold by other suppliers may be listed for expected applications.
- PNAS USA (1992) 89:6065-6069. (functional studies; ELISA)
- J Immunol (2005) 174:1063-1072. (ELISA, Flow)
Entrez Gene ID: 16189
Expected AB Applications: ELISA (published for clone)/Flow (intracellular) (published for clone)/Functional studies (published for clone)
Z-Antibody Applications: Flow, intracellular (published)/Functional studies (published)/ELISA (published)
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