Product Description: Incyclinide (CMT-3, COL-3) is a matrix metalloproteinase (MMP) inhibitor and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
Applications: Cancer-Kinase/protease
Formula: C19H17NO7
References: [1]Lee HM, et al. CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMPactivity: relevance to cancer. Curr Med Chem. 2001 Feb;8(3):257-60./[2]Liu Y, A chemically modified tetracycline (CMT-3) is a new antifungal agent. Antimicrob Agents Chemother. 2002 May;46(5):1447-54./[3]Bildt MM, et al. CMT-3 inhibits orthodontic tooth displacement in the rat. Arch Oral Biol. 2007 Jun;52(6):571-8.
CAS Number: 15866-90-7
Molecular Weight: 371.34
Compound Purity: 98.51
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL
Target: MMP