Indomethacin-d4, CAS 87377-08-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-(4-chlorobenzoyl-2,3,5,6-d4)-5-methoxy-2-methyl-1H-indole-3-acetic acid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C19H12ClD4NO4

Formula Weight: 361.81162

CAS Number: 87377-08-0

Notes: Indomethacin-d4 is intended for use as an internal standard for the quantification of indomethacin (Item No. 70270) by GC- or LC-MS. Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively).{1286} It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes.{37630} Indomethacin reduces ocular inflammation induced by bovine serum in rabbits.{37631} It also reduces paw edema in a rat model of carrageenan-induced inflammation.{37632}

• Artikelnummer: CAY25434-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25434-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung