INI-1 Monoclonal Antibody

Background: INI-1, located on chromosome 22q11.2, is a member of the SWI/SWF chromatin remodeling complex and is expressed in all normal tissues. INI-1 encodes a protein of HSWI/SNF chromatin remodeling complex with unknown function, which is prone to mutation and deletion in malignant rhabdoid tumors (MRT). "In most malignant rhabdoid tumors (including atypical teratoma/rhabdoid tumor of the central nervous system in children) and epithelioid sarcomas, INI-1 is inactivated, and the majority of medulloblastomas and primitive neuroectodermal tumors express INI-1."

• Artikelnummer: ELSELAB6932-M-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELAB6932-M-200
• Verpackungseinheit: 200μL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Wirt: Mouse
• Konjugat: Unconjugated