Clone: 23C6
Specificity: Recognizes the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
Antibody Modification: Unconjugated
Presentation: PBS, 0.09% Sodium Azide
Immunogen: Osteoclasts from osteoclastomas
Gene: Integrin Alpha V Beta 3
Description: Integrin Alpha V Beta 3 antibody LS-C45351 is an unconjugated mouse monoclonal antibody to human Integrin Alpha V Beta 3. Validated for Flow, IHC and IP.
Usage: Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Recommended Storage: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.