Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifuran]-5S-yl]-9-oxo-10Z,16E-docosadienoic acid, calcium salt
Purity: ≥98%
Formula Markup: C41H70O9 / Ca
Formula Weight: 747.1
CAS Number: 56092-82-1
Notes: Ionomycin is a calcium ionophore originally isolated from S. conglobatus.{19988} It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils.{58291} Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro.{58292,58293}
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