IOWH-032, CAS 1191252-49-9

IOWH-032, CAS 1191252-49-9
Artikelnummer
MEXHY-18337-10.1
Verpackungseinheit
10 mM/1 ml
Hersteller
MedChemExpress

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Product Description: IOWH-032 is a a synthetic anti-secretory molecule, is a potent CFTR inhibitor with an IC50 value of 8 μM. IOWH-032 also is a anti-diarrheal agent[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C22H15Br2N3O4

References: [1]Doyle K, et al. Inhibitors Of The CFTR Chloride Ion Channel As Potential Treatment For Acute Secretory Diarrhea: Development Of 5-membered Heterocycles Suitable For Pre-clinical Evaluation/[2]de Hostos EL, et al. Developing novel antisecretory drugs to treat infectious diarrhea. Future Med Chem. 2011 Aug;3(10):1317-25./[3]Lotti V, et al. CFTR Modulation Reduces SARS-CoV-2 Infection in Human Bronchial Epithelial Cells. Cells. 2022 Apr 15;11(8):1347./[4]Thiagarajah JR, et al. CFTR inhibitors for treating diarrheal disease. Clin Pharmacol Ther. 2012 Sep;92(3):287-90.

CAS Number: 1191252-49-9

Molecular Weight: 545.18

Compound Purity: 99.63

Research Area: Infection; Metabolic Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: CFTR;SARS-CoV
Mehr Informationen
Artikelnummer MEXHY-18337-10.1
Hersteller MedChemExpress
Hersteller Artikelnummer HY-18337-10.1
Verpackungseinheit 10 mM/1 ml
Mengeneinheit STK
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