IQ-1, CAS 331001-62-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide

Purity: ≥98%

Formula Markup: C21H22N4O2

Formula Weight: 362.4

CAS Number: 331001-62-8

Notes: IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse embryonic stem cell (ESC) pluripotency.{26541} When used at 4 µg/ml with Wnt3a, it allows ESCs to form embryoid bodies that continue to express markers of pluripotency, including α-fetoprotein and β-III tubulin.{26541} IQ-1 blocks the interaction of the protein Naked cuticle with a subunit of the protein phosphatase PP2A, altering signaling through Wnt/β-catenin and maintaining the expression of stem cell markers Oct4, Nanog, and Rex1 in ESCs.{26541}

• Artikelnummer: CAY16153-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16153-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK