Iso-PPADS (tetrasodium), CAS 207572-67-6

Product Description: Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC50s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI)[1][2].

Applications: COVID-19-immunoregulation

Formula: C14H10N3Na4O12PS2

References: [1]González-López A, et al. Lung Purinoceptor Activation Triggers Ventilator-Induced Brain Injury. Crit Care Med. 2019 Nov;47(11):e911-e918./[2]Brown SG, et al. Actions of a Series of PPADS Analogs at P2X1 and P2X3 Receptors. Drug Dev Res. 2001 Aug;53(4):281-291.

CAS Number: 207572-67-6

Molecular Weight: 599.30

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: P2X Receptor

• Artikelnummer: MEXHY-101077-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-101077-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK