Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (3ß,5ß)-3-hydroxy-cholan-24-oic acid
Purity: ≥95%
Formula Markup: C24H40O3
Formula Weight: 376.5726
CAS Number: 1534-35-6
Notes: Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithocholic acid (LCA; Item No. 20253) or lithocholic acid 3α-sulfate (Item No. 20676).{54013,43814} Isolithocholic acid (0.01%) inhibits spore germination induced by taurocholic acid (TCA; Item No. 16215) in the C. difficile strains CD196, M68, BI9, and 630, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.0003%.{54006} Fecal levels of isolithocholic acid are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.{54007}