IXA4, CAS 1185329-96-7

Product Description: IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation[1].

Applications: Neuroscience-Neurodegeneration

Formula: C24H28N4O4

References: [1]Grandjean JMD, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020;16(10):1052-1061.

CAS Number: 1185329-96-7

Molecular Weight: 436.50

Compound Purity: 98.83

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: IRE1

• Artikelnummer: MEXHY-139214-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-139214-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK