Product Description: Izilendustat is a potent inhibitor of prolyl hydroxylase which can stabilize hypoxia inducible factor- 1 alpha (HIF- lα) and hypoxia inducible factor-2 (HIF-2). Izilendustat has the potential for researching diseases that relate to the body’s inmmune response like colitis and other inflammatory bowel diseases (extracted from patent WO2011057115A1 and WO2011057121A1)[1][1].
Applications: COVID-19-immunoregulation
Formula: C22H28ClN3O4
References: [1]Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1. /[2]Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.
CAS Number: 1303512-02-8
Molecular Weight: 433.936
Compound Purity: 99.20
Research Area: Inflammation/Immunology; Cardiovascular Disease
Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)