JNJ 10181457 dihydrochloride, CAS 544707-20-2

Product Description: JNJ-10181457 is a neutral, potent, brain-penetrant and selective non-imidazole H3 antagonist which increases NE and ACh concentrations in rat frontal cortex. JNJ-10181457 can be used for neurological research[1].

Applications: Neuroscience-Neuromodulation

Formula: C20H30Cl2N2O

References: [1]Galici R, et al. JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition. Neuropharmacology. 2009 Jun;56(8):1131-7.

CAS Number: 544707-20-2

Molecular Weight: 385.37

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Histamine Receptor

• Artikelnummer: MEXHY-107562-500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-107562-500UG
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK