Product Description: JNJ-42165279 is an orally active FAAH inhibitor, with IC50 values of 70 nM for hFAAH and 313 nM for rFAAH. JNJ-42165279 can be used in research related to the field of neuropathic pain[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C18H17ClF2N4O3
References: [1]Keith JM, et al. Preclinical Characterization of the FAAH Inhibitor JNJ-42165279. ACS Med Chem Lett. 2015 Nov 2;6(12):1204-8./[2]van Heerden M, et al. Exacerbation of Background Nuclear Cataracts in Sprague-Dawley Rats in Embryo-Fetal Development Studies With JNJ-42165279, a Fatty Acid Amide Hydrolase Inhibitor. Toxicol Pathol. 2021 Aug;49(6):1193-1205.
CAS Number: 1346528-50-4
Molecular Weight: 410.80
Compound Purity: 99.87
Research Area: Neurological Disease
Solubility: DMSO : ≥ 100 mg/mL
Target: Autophagy;FAAH