JNJ-47117096, CAS 1610586-62-3

Product Description: JNJ-47117096 is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM[1].

Formula: C21H22N4O2

References: [1]Johnson CN, et al. Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase. ACS Med Chem Lett. 2014 May 23;6(1):25-30./[2]Beke L, et al. MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells. Biosci Rep. 2015 Oct 2;35(6). pii: e00267.

CAS Number: 1610586-62-3

Molecular Weight: 362.43

Research Area: Cancer

Target: FLT3;MELK

• Artikelnummer: MEXHY-12420A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-12420A-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK