KAN0438757, CAS 1451255-59-6

Product Description: KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM[1].

Applications: Cancer-Kinase/protease

Formula: C21H18FNO7S

References: [1]Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872./[2]De Oliveira T, et al. Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo. Cancers (Basel). 2021 Feb 28;13(5):1011.

CAS Number: 1451255-59-6

Molecular Weight: 447.43

Compound Purity: 99.41

Research Area: Cancer

Solubility: DMSO : 130 mg/mL (ultrasonic)

Target: Autophagy

• Artikelnummer: MEXHY-112808-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-112808-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK