Ketorolac-d5, CAS 1215767-66-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 5-(benzoyl-d5)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

Purity: ≥99% deuterated forms (d1-d5)

Formula Markup: C15H8D5NO3

Formula Weight: 260.29896

CAS Number: 1215767-66-0

Notes: Ketorolac-d5 is intended for use as an internal standard for the quantification of ketorolac (Item No. 9001148) by GC- or LC-MS. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) and a non-selective COX inhibitor (IC50 = 20 nM for both COX-1 and COX-2).{6065} It prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases prostaglandin E2 (PGE2) levels in paw tissue in a mouse model of carrageenan-induced inflammation when administered at a dose of 30 mg/kg. Ketorolac is a racemic mixture containing the active (S)-ketorolac (Item No. 11348) and inactive (R)-ketorolac enantiomers. Formulations containing ketorolac have been used to manage postoperative pain and as ophthalmic solutions to treat ocular pain and inflammation.

• Artikelnummer: CAY26454-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26454-500
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung