KF38789, CAS 257292-29-8

Shelf life (days): 1460

Info: An inhibitor of P-selectin-mediated cell adhesion; inhibits U937 cell binding to immobilized P-selectin immunoglobin (IC50 = 1.97 µM); selective for P-selectin-mediated cell adhesion over E- and or L-selectin-mediated adhesion of U937 and HL-60 cells, respectively, at 100 µM; decreases P-selectin-induced superoxide production by isolated human PMNs at 0.1-10 µM; reduces the proliferation of T47D and HCT116 cells (EC50s = 0.41 and 0.56 µM, respectively); reduces PMN infiltration into the peritoneum in a mouse model of thioglycollate-induced peritonitis at 1 mg/kg

Formulation: A solid

Formal Name: 3-[7-(2,4-dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one

Purity: ≥98%

Formula Markup: C19H21NO5S

Formula Weight: 375.439

CAS Number: 257292-29-8

• Artikelnummer: CAY43182-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 43182-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK