KI-696, CAS 1799974-70-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: ßS-[3-[[(4R)-3,4-dihydro-4-methyl-1,1-dioxido-2H-5,1,2-benzoxathiazepin-2-yl]methyl]-4-methylphenyl]-7-methoxy-1-methyl-1H-benzotriazole-5-propanoic acid

Purity: ≥98%

Formula Markup: C28H30N4O6S

Formula Weight: 550.62716

CAS Number: 1799974-70-1

Notes: A Keap1-Nrf2 protein-protein interaction inhibitor; binds to the Keap1 Kelch domain (Kd = 1.3 nM) and increases the accumulation of Nrf2 in isolated human bronchial epithelial cells in a concentration-dependent manner; increases the expression of NQO1, GCLM, HMOX1, and TXNRD1 in bronchial epithelial cells isolated from patients with COPD (EC50s = 22, 36, 16, and 27 nM, respectively); increases lung expression of Nqo1, Hmox1, and Txnrd1 in rats at 50 µmol/kg

• Artikelnummer: CAY42039-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42039-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK