KN-62, CAS 127191-97-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 5-isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester

Purity: ≥98%

Formula Markup: C38H35N5O6S2

Formula Weight: 721.9

CAS Number: 127191-97-3

Notes: KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII; IC50 = 900 nM).{17252} It does not affect the activity of several other kinases when tested at 10 µM.{12847} KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).{17253}

• Artikelnummer: CAY13318-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13318-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK