Product Description: KRN-633 is a potent VEGFR inhibitor with IC50s of 170, 160 and 125 nM for VEGFR1, VEGFR2 and VEGFR3, respectively.
Applications: Cancer-Kinase/protease
Formula: C20H21ClN4O4
References: [1]Nakamura K, et al. KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. Mol Cancer Ther. 2004 Dec;3(12):1639-49.
CAS Number: 286370-15-8
Molecular Weight: 416.86
Compound Purity: 99.45
Research Area: Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: VEGFR