Kukoamine B, CAS 164991-67-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-(3-aminopropyl)-N-[4-[[3-[[3-(3,4-dihydroxyphenyl)-1-oxopropyl]amino]propyl]amino]butyl]-3,4-dihydroxy-benzenepropanamide

Purity: ≥95%

Formula Markup: C28H42N4O6

Formula Weight: 530.7

CAS Number: 164991-67-7

Notes: Kukoamine B is a spermine alkaloid first isolated from a traditional Chinese herb L. chinense that inhibits both lipopolysaccharides (LPS) and oligodeoxynucleotides containing CpG motifs (CpG DNA).{33457} It is reported to inhibit proinflammatory signal transduction and cytokine expression induced by LPS and CpG DNA (Kds = 1.24 and 0.66 µM).{33457} LPS and CpG DNA are two well-recognized pathogen-associated molecular patterns (PAMPs) that play a role in triggering sepsis, thus sepsis may be attenuated by simultaneously neutralizing LPS and CpG DNA.{33457}

• Artikelnummer: CAY21091-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21091-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK