Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N-[4-[[[(6S)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, monocalcium salt, hydrate
Purity: ≥98%
Formula Markup: C20H21N7O7 / Ca [XH2O]
Formula Weight: 471.42372
Notes: L-Folinic acid is a reduced folic acid and isomer of DL-folinic acid (Item No. 20383).{40766} Formulations containing DL-folinic acid, a racemic mixture of D-folinic acid and L-folinic acid, that have been used to prevent toxicity following therapy with high-dose methotrexate, to enhance the antitumor activity of 5-fluorouracil, and as a folate supplement.{32087,25271} Clinical studies demonstrate that formulations containing L-folinic acid have similar efficacy and tolerability as those contianing DL-folinic acid and have been used interchangeably for modification of antitumor activity of 5-fluorouracil, while D-folinic acid is inactive.{40766}
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