Shelf life (days): 1460.0
Formulation: A solid
Formal Name: L-leucine-2,3,3,4,5,5,5,5',5',5'-d10
Purity: ≥99% deuterated forms (d1-d10)
Formula Markup: C6H3D10NO2
Formula Weight: 141.23356
CAS Number: 106972-44-5
Notes: L-Leucine-d10 is intended for use as an internal standard for the quantification of L-leucine (Item No. 34342) by GC- or LC-MS. L-Leucine is an essential amino acid.{57686} It increases basal insulin secretion and decreases glucose-induced insulin release in INS-1E rat insulinoma cells when used at concentrations of 1, 5, and 10 mM.{57687} L-Leucine (1, 5, and 10 mM) decreases triglyceride levels and increases cholesterol accumulation in INS-1E cells. It stimulates skeletal muscle protein synthesis in exercised rats, as well as in food-deprived rats in an mTOR-dependent manner.{57688,57689} Formulations containing L-leucine have been used as dietary supplements.
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