Product Description: Lansoprazole sulfide is an active metabolite of Lansoprazole (HY-13662) by cytochrome P450, possesses anti-cancer activity. Lansoprazole sulfide is an anti-tuberculous agent, with an IC50 of 0.59 µM for M. tb[1].
Formula: C16H14F3N3OS
References: [1]Jenny Beebe, et al. Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase. J Med Chem. 2022 Oct 27;65(20):13681-13691./[2]Sipho Mdanda, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12).
CAS Number: 103577-40-8
Molecular Weight: 353.37
Compound Purity: 99.91
Research Area: Cancer; Inflammation/Immunology
Target: Bacterial;Drug Metabolite