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Encompassing Amino Acids: 64-269(end)
Application: Useful as a kinase substrate and for screening small molecules and antibodies.
Description: Human linker for activation of T cells family member 1 (LAT), also known as 36 kDa phospho-tyrosine adapter protein, pp36. GenBank Accession No. NM_001014989* variant 4, a.a. 64-269(end), with N-terminal His-tag, expressed in an E. coli expression system. MW = 24.4 kDa. This protein runs at a higher MW by SDSPAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 40 mM Tris pH 8.0, 110 mMNaCl, 2.2 mM KCl, 0.04% Tween-20, 20%glycerol and 3 mM DTT.
Genbank: NM_001014989*
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: O43561
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Zhang, W. et al., Cell. 1998; 92(1): 83- 92.
2. Balagopalan, L. et al., J. Immunol. 2013; 190(8): 3849-53.
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