LLY-283, CAS 2040291-27-6

Product Description: LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.

Applications: Cancer-programmed cell death

Formula: C17H18N4O4

References: [1]Zahid Q. Bonday, et al. LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med. Chem. Lett., 2018, 9 (7), pp 612-617.

CAS Number: 2040291-27-6

Molecular Weight: 342.35

Compound Purity: 99.22

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 3.57 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Histone Methyltransferase

• Artikelnummer: MEXHY-107777-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-107777-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK