Product Description: LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 [1].
Applications: Cancer-programmed cell death
Formula: C36H42N6O
References: [1]Nguyen H, et al. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J Biol Chem. 2015 May 29;290(22):13641-13653.
CAS Number: 1793053-37-8
Molecular Weight: 574.76
Compound Purity: 98.28
Research Area: Cancer
Solubility: DMSO : 15 mg/mL (ultrasonic;warming)
Target: Histone Methyltransferase