LUF6283, CAS 92933-48-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 5-butyl-1H-pyrazole-3-carboxylic acid

Purity: ≥98%

Formula Markup: C8H12N2O2

Formula Weight: 168.2

CAS Number: 92933-48-7

Notes: LUF6283 is a partial agonist of GPR109A/HCA2 G protein-coupled receptors (Ki = 0.55 μM in a radioligand binding assay).{42585} It stimulates [35S]-GTPγS binding and increases phosphorylation of ERK in HEK293T cells expressing GPR109A/HCA2 receptors (EC50s = 3.1 and 0.32 μM, respectively). In vivo, LUF6283 (400 mg/kg per day) reduces plasma levels of VLDL and hepatic expression of apolipoprotein B in mice.

• Artikelnummer: CAY15423-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 15423-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK