Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-[5-[3,5-bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]-benzoic acid
Purity: ≥95%
Formula Markup: C36H42N4O3
Formula Weight: 578.7
CAS Number: 1433497-19-8
Notes: LY2955303 is a potent antagonist of retinoic acid receptor γ (RARγ; Ki = 1.1 nM).{42717} It is selective for RARγ over RARα and RARβ (Kis = >1,700 and >2,980 nM, respectively). LY2955303 reduces differential weight bearing between the contralateral and ipsilateral limbs in a rat model of monoiodoacetate-induced osteoarthritis (ED50 = 0.72 mg/kg).