M6903

Product Description: M6903 is a humanized monoclonal IgG2 antibody targeting T cell immunoglobulin and mucin domain-3 (TIM-3) (KD for human TIM-3 is 2.3 nM). M6903 binds to TIM-3, blocking the binding of TIM-3 to phosphatidylserine (PtdSer), carcinoembryonic antigen cell adhesion-related molecule 1 (CEACAM1), and galectin 9 (Gal-9), thus relieving TIM-3-mediated T cell inhibition and exerting the activities of activating antigen-specific T cells and enhancing anti-tumor immunity. M6903 is promising for research of cancers[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Zhang D, et al. Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology. 2020 Apr 1;9(1):1744921.

Molecular Weight: N/A

Research Area: Cancer

Target: Tim3

• Artikelnummer: MEXHY-P991198-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P991198-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK
• Konjugat: Unconjugated