MC3343, CAS 1535187-91-7

Shelf life (days): 1460

Info: A DNA methyltransferase inhibitor (IC50s = 9 and 2.8 µM for DNMT1 and the DNMT3A2/DNMT3L complex, respectively); selective for these DNMTs over PRMT1 and G9a-like protein; selectively decreases the viability of U937, Raji, PC3, and MDA-MB-231 cancer cells over isolated PBMCs (IC50s = 4.3, 8.8, 6.6, 9.7, and 57.4 µM, respectively); decreases tumor volume in a PDX mouse model of osteosarcoma at 50 mg/kg when used alone or in combination with doxorubicin

Formulation: A solid

Formal Name: N-[3-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-3-(4-quinolinylamino)-benzamide

Purity: ≥98%

Formula Markup: C27H23N7O

Formula Weight: 461.529

CAS Number: 1535187-91-7

• Artikelnummer: CAY43331-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 43331-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK