MDM2(MDM2/2414), CF740 conjugate, 0.1mg/mL

MDM2(MDM2/2414), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC742414-500
Verpackungseinheit
500 uL
Hersteller
Biotium

Verfügbarkeit: wird geladen...
Preis wird geladen...
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: MDM2/2414

Immunogen: Recombinant human MDM2 protein fragment (around aa 126-254) (exact sequence is proprietary)

Antibody Reactivity: MDM2

Entrez Gene ID: 4193

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
Mehr Informationen
Artikelnummer BTMBNC742414-500
Hersteller Biotium
Hersteller Artikelnummer BNC742414-500
Verpackungseinheit 500 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry
Isotyp IgG1 kappa
Wirt Mouse
Konjugat Conjugated, CF740
Produktinformation (PDF) Download
MSDS (PDF) Download