Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5-[[3,5-di(methyl-d3)phenoxy]methyl]-2-oxazolidinone
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C12H9D6NO3
Formula Weight: 227.2888
CAS Number: 1189944-95-3
Notes: Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone (Item No. 15777) by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant.{25864,58285} It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM.{58285} Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 (PGE2; Item No. 14010) in RAW 264.7 cells. Formulations containing metaxalone have been used in the treatment of lower back pain.
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