Methylpiperidino pyrazole, CAS 289726-02-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[1-(4-hydroxyphenyl)-4-methyl-5-[4-[2-(1-piperidinyl)ethoxy]phenyl]-1H-pyrazol-3-yl]-phenol

Purity: ≥98%

Formula Markup: C29H31N3O3

Formula Weight: 469.6

CAS Number: 289726-02-9

Notes: Estrogen action is mediated through two estrogen receptor (ER) subtypes, ERα and ERβ, which have distinct target tissue distributions and functional activities.{10559} Methylpiperidino pyrazole is an ER antagonist that is highly selective for ERα compared to ERβ (Kis = 5.6 nM and 2.3 μM, respectively).{21951} It can inhibit ERα transcriptional activation with an IC50 value of 80 nM.{21949} It has been used to evaluate the role of ERα in various estrogen-responsive systems, including certain cancers.{21950}

• Artikelnummer: CAY13863-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13863-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK