MID-1, CAS 312608-54-1

Product Description: MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C12H11N3O4S

References: [1]Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.

CAS Number: 312608-54-1

Molecular Weight: 293.30

Compound Purity: 99.36

Research Area: Metabolic Disease

Solubility: DMSO : 31.25 mg/mL (ultrasonic)

Target: Insulin Receptor

• Artikelnummer: MEXHY-115461-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-115461-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK