Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 1-methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide
Purity: ≥98%
Formula Markup: C39H46N2P / 3I
Formula Weight: 954.5
CAS Number: 1821370-28-8
Notes: MitoPQ is comprised of a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat.{30305} Driven by membrane potential, it accumulates selectively in the mitochondrial matrix where it produces superoxide by redox cycling at the flavin site of complex I.{30305} Thus, MitoPQ selectively increases superoxide production within mitochondria and can be used as a tool either in cells or in vivo to investigate the role of mitochondrial superoxide in pathology and redox signaling.{30305}