Product Description: MK-5108 is a highly potent and specific inhibitor of Aurora A kinase with an IC50 value of 0.064 nM.
Applications: Cancer-Kinase/protease
Formula: C22H21ClFN3O3S
References: [1]Shimomura T, et al. MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel. Mol Cancer Ther. 2010 Jan;9(1):157-66.
CAS Number: 1010085-13-8
Molecular Weight: 461.94
Compound Purity: 99.89
Research Area: Cancer
Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)