MK-8245, CAS 1030612-90-8

Product Description: MK-8245 is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C17H16BrFN6O4

References: [1]Oballa RM, et al. Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.J Med Chem. 2011 Jul 28;54(14):5082-96. Epub 2011 Jun 28.

CAS Number: 1030612-90-8

Molecular Weight: 467.25

Compound Purity: 99.04

Research Area: Metabolic Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: Stearoyl-CoA Desaturase (SCD)

• Artikelnummer: MEXHY-13070-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-13070-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK